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See allImportant Safety Information for Wegovy (semaglutide) injection
Caution: Risk of Thyroid C-Cell Tumors
In animal studies involving mice and rats, semaglutide (the active component in Ozempic and Wegovy) was associated with thyroid tumors, including thyroid cancer. It is uncertain whether Ozempic may lead to thyroid tumors or a specific thyroid cancer called medullary thyroid carcinoma (MTC) in humans. If you notice any neck lumps, swelling, hoarseness, difficulty swallowing, or shortness of breath, please inform your healthcare provider. These could be signs of thyroid cancer.
Do not use Wegovy if you or any family member has a history of medullary thyroid carcinoma (MTC) or a condition known as Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
What is the FDA-approved use of Wegovy?
Ozempic is a glucagon-like peptide-1 (GLP-1) receptor agonist used for:
- Enhancing glycemic control in patients with type 2 diabetes mellitus, alongside diet and exercise.
- Reducing the risk of major cardiovascular events in patients with type 2 diabetes mellitus and established cardiovascular disease.
Limitations of Use:
- Wegovy has not been studied in patients with a history of pancreatitis.
- Wegovy is not intended for treating type 1 diabetes mellitus.
- Your JRNYS-affiliated provider may suggest Wegovy for chronic weight management (obesity or overweight).
Who should avoid Wegovy?
Do not use Wegovy if:
- You or any family member has a history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
- You have known allergies to semaglutide (the active ingredient in Wegovy or Ozempic).
How should Ozempic be administered?
Ozempic can be taken with or without food. The pre-filled injector pen is self-administered as a subcutaneous injection in the stomach, thigh, or upper arm once a week on the same day each week.
Your JRNYS-affiliated provider will guide you on the treatment plan, which may include dose increases every four weeks.
Do not alter your dosing regimen or discontinue Wegovy without consulting your provider first.
What should I inform my JRNYS-affiliated provider before using Wegovy?
Ozempic can interact with certain medications. It's crucial to disclose all current medications, including prescription, over-the-counter drugs, vitamins, herbal supplements, and dietary supplements to your JRNYS-affiliated provider.
Some medications to be aware of include:
- Drugs for type 1 or type 2 diabetes, such as insulin or sulfonylureas (e.g., Amaryl or Glucotrol XL).
- Wegovy can delay gastric emptying, potentially affecting the absorption of orally taken medications. Your provider can advise on scheduling your medications.
Additionally, share your complete medical history with your provider, especially if you have a history of:
- Type 1 or type 2 diabetes
- Thyroid cancer
- Pancreatitis
- Kidney disease
- Diabetic retinopathy
- Depression
- Suicidal thoughts or behavior
Notify your provider if you are pregnant, planning to become pregnant, or breastfeeding.
If pregnant: Wegovy should not be used during pregnancy. Animal studies suggest potential risks to the unborn baby from Wegovy exposure during pregnancy. Weight loss during pregnancy is not beneficial and may harm the baby.
If of reproductive potential: Discontinue Wegovy at least two months before planned pregnancy, as the drug may persist in the bloodstream.
If breastfeeding: Wegovy was detected in the milk of lactating rats. Inform your JRNYS-affiliated provider if you are breastfeeding before starting Wegovy.
Pregnancy registry: A pregnancy exposure registry monitors outcomes in women exposed to semaglutide (the active ingredient in Wegovy) during pregnancy.
Pregnant women exposed to semaglutide and healthcare providers can contact Novo Nordisk at 1-800-727-6500.
Withholding or providing inaccurate health information to obtain treatment may lead to harm, including death.
What are the most serious side effects to monitor for while taking Wegovy?
If you experience a medical emergency, call 911 or seek immediate medical attention.
Serious side effects associated with Wegovy include:
- Thyroid C-Cell Tumors: While Wegovy's impact on human thyroid C-cell tumors remains uncertain, animal studies revealed an increase in thyroid C-cell tumors, including MTC. Ozempic is contraindicated for patients with a family history of MTC or MEN 2. Notify your provider if you notice neck lumps, swelling, hoarseness, difficulty swallowing, or shortness of breath, as these may indicate thyroid cancer.
- Acute Pancreatitis: Be vigilant for signs of acute pancreatitis, such as persistent severe abdominal pain, possibly radiating to the back, with or without vomiting.
- Diabetic Retinopathy Complications in Patients with Type 2 Diabetes: If you have type 2 diabetes, promptly inform your provider of any changes in vision.
- Never Share a Pen: Sharing Wegovy pens can lead to infections.
- Low Blood Sugar (Hypoglycemia): Wegovy can lower blood glucose, potentially causing low blood sugar in patients with type 2 diabetes using other glucose control medications. Monitor blood sugar levels and watch for signs of low blood sugar, including dizziness, blurred vision, mood changes, sweating, or rapid heartbeat.
- Acute Kidney Injury: In individuals with kidney issues, dehydration from diarrhea, nausea, and vomiting can worsen kidney problems. Ensure adequate hydration to reduce the risk of dehydration.
- Serious Allergic Reactions: Discontinue Wegovy immediately if you experience symptoms of a severe allergic reaction, such as facial swelling, severe rash, rapid heartbeat, breathing difficulties, or fainting.
- Acute Gallbladder Disease: Wegovy may lead to gallbladder problems, including gallstones. Some issues may require surgery. Inform your provider of upper stomach pain, yellowing of skin or eyes (jaundice), fever, or pale stools.
- Increase in Heart Rate: Notify your provider of a rapid resting heart rate.
- Suicidal Behavior and Ideation: Monitor your mental health for sudden changes in mood, behavior, thoughts, or feelings. If you experience new, worsening, or concerning mental changes, contact your healthcare provider promptly.
What are the most common side effects of Wegovy?
Common side effects of Wegovy include:
- Nausea
- Vomiting
- Diarrhea
- Stomach pain
- Constipation
If you experience adverse effects, please report them:
- Contact Novo Nordisk Inc. at 1-833-934-6891
- Contact FDA MedWatch at 1-800-FDA-1088 or visit www.fda.gov/medwatch
This information is not exhaustive. Refer to the full Prescribing Information for complete safety details.
Important Safety Information for Ozempic (semaglutide) injection
Caution: Risk of Thyroid C-Cell Tumors
In animal studies involving mice and rats, semaglutide (the active component in Ozempic and Wegovy) was associated with thyroid tumors, including thyroid cancer. It is uncertain whether Ozempic may lead to thyroid tumors or a specific thyroid cancer called medullary thyroid carcinoma (MTC) in humans. If you notice any neck lumps, swelling, hoarseness, difficulty swallowing, or shortness of breath, please inform your healthcare provider. These could be signs of thyroid cancer.
Do not use Ozempic if you or any family member has a history of medullary thyroid carcinoma (MTC) or a condition known as Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
What is the FDA-approved use of Ozempic?
Ozempic is a glucagon-like peptide-1 (GLP-1) receptor agonist used for:
- Enhancing glycemic control in patients with type 2 diabetes mellitus, alongside diet and exercise.
- Reducing the risk of major cardiovascular events in patients with type 2 diabetes mellitus and established cardiovascular disease.
Limitations of Use:
- Ozempic has not been studied in patients with a history of pancreatitis.
- Ozempic is not intended for treating type 1 diabetes mellitus.
- Your JRNYS-affiliated provider may suggest Ozempic for chronic weight management (obesity or overweight).
Who should avoid Ozempic?
Do not use Ozempic if:
- You or any family member has a history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
- You have known allergies to semaglutide (the active ingredient in Wegovy or Ozempic).
How should Ozempic be administered?
Ozempic can be taken with or without food. The pre-filled injector pen is self-administered as a subcutaneous injection in the stomach, thigh, or upper arm once a week on the same day each week.
Your JRNYS-affiliated provider will guide you on the treatment plan, which may include dose increases every four weeks.
Do not alter your dosing regimen or discontinue Ozempic without consulting your provider first.
What should I inform my JRNYS-affiliated provider before using Ozempic?
Ozempic can interact with certain medications. It's crucial to disclose all current medications, including prescription, over-the-counter drugs, vitamins, herbal supplements, and dietary supplements to your JRNYS-affiliated provider.
Some medications to be aware of include:
- Drugs for type 1 or type 2 diabetes, such as insulin or sulfonylureas (e.g., Amaryl or Glucotrol XL).
- Ozempic can delay gastric emptying, potentially affecting the absorption of orally taken medications. Your provider can advise on scheduling your medications.
Additionally, share your complete medical history with your provider, especially if you have a history of:
- Type 1 or type 2 diabetes
- Thyroid cancer
- Pancreatitis
- Kidney disease
- Diabetic retinopathy
- Depression
- Suicidal thoughts or behavior
Notify your provider if you are pregnant, planning to become pregnant, or breastfeeding.
If pregnant: Ozempic should not be used during pregnancy. Animal studies suggest potential risks to the unborn baby from Ozempic exposure during pregnancy. Weight loss during pregnancy is not beneficial and may harm the baby.
If of reproductive potential: Discontinue Ozempic at least two months before planned pregnancy, as the drug may persist in the bloodstream.
If breastfeeding: Ozempic was detected in the milk of lactating rats. Inform your JRNYS-affiliated provider if you are breastfeeding before starting Ozempic.
Pregnancy registry: A pregnancy exposure registry monitors outcomes in women exposed to semaglutide (the active ingredient in Ozempic and Ozempic) during pregnancy.
Pregnant women exposed to semaglutide and healthcare providers can contact Novo Nordisk at 1-800-727-6500.
Withholding or providing inaccurate health information to obtain treatment may lead to harm, including death.
What are the most serious side effects to monitor for while taking Ozempic?
If you experience a medical emergency, call 911 or seek immediate medical attention.
Serious side effects associated with Ozempic include:
- Thyroid C-Cell Tumors: While Ozempic's impact on human thyroid C-cell tumors remains uncertain, animal studies revealed an increase in thyroid C-cell tumors, including MTC. Ozempic is contraindicated for patients with a family history of MTC or MEN 2. Notify your provider if you notice neck lumps, swelling, hoarseness, difficulty swallowing, or shortness of breath, as these may indicate thyroid cancer.
- Acute Pancreatitis: Be vigilant for signs of acute pancreatitis, such as persistent severe abdominal pain, possibly radiating to the back, with or without vomiting.
- Diabetic Retinopathy Complications in Patients with Type 2 Diabetes: If you have type 2 diabetes, promptly inform your provider of any changes in vision.
- Never Share a Pen: Sharing Ozempic pens can lead to infections.
- Low Blood Sugar (Hypoglycemia): Ozempic can lower blood glucose, potentially causing low blood sugar in patients with type 2 diabetes using other glucose control medications. Monitor blood sugar levels and watch for signs of low blood sugar, including dizziness, blurred vision, mood changes, sweating, or rapid heartbeat.
- Acute Kidney Injury: In individuals with kidney issues, dehydration from diarrhea, nausea, and vomiting can worsen kidney problems. Ensure adequate hydration to reduce the risk of dehydration.
- Serious Allergic Reactions: Discontinue Ozempic immediately if you experience symptoms of a severe allergic reaction, such as facial swelling, severe rash, rapid heartbeat, breathing difficulties, or fainting.
- Acute Gallbladder Disease: Ozempic may lead to gallbladder problems, including gallstones. Some issues may require surgery. Inform your provider of upper stomach pain, yellowing of skin or eyes (jaundice), fever, or pale stools.
- Increase in Heart Rate: Notify your provider of a rapid resting heart rate.
- Suicidal Behavior and Ideation: Monitor your mental health for sudden changes in mood, behavior, thoughts, or feelings. If you experience new, worsening, or concerning mental changes, contact your healthcare provider promptly.
What are the most common side effects of Ozempic?
Common side effects of Ozempic include:
- Nausea
- Vomiting
- Diarrhea
- Stomach pain
- Constipation
If you experience adverse effects, please report them:
- Contact Novo Nordisk Inc. at 1-833-934-6891
- Contact FDA MedWatch at 1-800-FDA-1088 or visit www.fda.gov/medwatch
This information is not exhaustive. Refer to the full Prescribing Information for complete safety details.
A 360 
approach to health
-
Custom GLP-1 treatment plans tailored to your unique weight loss goals -
Insurance navigation & 24/7 support from our medical team
-
Optional nutritional coach & meal delivery services
-
Up to 31% less body fat mass*
*JRNYS members following our trizepatide protocol experienced outcomes consistent with the Surpass-1 trial, which showed up to a 31% reduction in fat mass over a 6-month period. Results may vary.
A 360 approach to health
“JRNYS is the only fully customized weight loss platform on the market.”
Dr. Henry Legere, Founder & Chief Medical Officer
Dr. Henry Legere is a Columbia-trained physician, Harvard immunologist, and serial healthcare entrepreneur shaping the future of digital medicine and longevity.
What are GLP-1s?
GLP-1s are ground breaking weight loss medications that work differently from older generations like phentermine.
They focus on important metabolic pathways to achieve sustainable weight loss. JRNYS providers prescribe various GLP-1 medications, including tirzepatide, semaglutide and liraglutide, which you might recognize as Wegovy®, Saxenda®, Ozempic®, or Mounjaro®.
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it works
We help you lose weight with revolutionary medication, concierge medical support, nutritional coach support, optional meal planning & more
Today
Today
Share information about your health & goals
In 1-2 Days
In 1-2 Days
Connect with a provider to determine your custom protocol
In 3-5 Days
In 3-5 Days
Receive your prescription, if approved. Pick up at your local pharmacy or choose discreet home delivery.
In 5-7 Days
In 5-7 Days
Pick up your medication and begin your program
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to improve their lifestyles
"I was never petite and was considered overweight by age 14. The challenge intensified after having three children and navigating the pandemic, leading to a significant struggle with weight loss. My turning point came with JRNYS, which reignited my internal motivation. I was prescribed Mounjaro (the same drug as Zepbound/Tirzepatide), and the results have been transformative—I've lost over 40 pounds in the past seven months. This journey feels like just the beginning. I'm now enthusiastic about going to the gym and am on a path to completely revitalize my life."
"Initially, I weighed 185 pounds at a height of 5 feet 7 inches, and I was struggling with pre-diabetes and PCOS, urgently seeking effective solutions. Within a week of consulting my JRNYS doctors, they managed to get GLP-1 receptor agonists prescribed for me. Since embarking on this treatment program, I have experienced significant progress, losing close to 60 pounds to date. This journey has not only been about weight loss but also about regaining control over my health and confronting the challenges posed by pre-diabetes and PCOS head-on."
“My wife gave me shit for years because my core wasn’t strong enough to stand on a paddle board. Now that I’ve lost 60lbs and strengthened my core I look great but still can’t stand on a paddle board”.
"After the pandemic, I found myself at the heaviest weight I'd ever been, nearly 160 pounds. The impact of COVID-19 was severe, leaving me with fatigue that lasted almost three months. Determined to make a change, I committed to regular exercise and joined the JRNYS program. My doctors prescribed me Mounjaro (also known as Tirzepatide or Zepbound) and it worked within the first week. This combination of physical activity and structured guidance transformed my life. Remarkably, I managed to reduce my weight to 123 pounds and fit into a size 2, a milestone I had never achieved in my adult life. This journey was not just about losing weight; it was about overcoming unprecedented challenges and reaching a state of health and confidence I never thought possible."
Throughout my life, I never really focused on eating healthily or maintaining a fit lifestyle, and this started to take a toll on me in my 30s. I found myself unable to play sports with the same vigor and felt a general sense of slowing down. However, that all changed with the JRNYS program. Surprisingly, without any significant changes to my lifestyle other than the program, I managed to lose close to 30 pounds. This weight loss has given me a lot more energy, rejuvenating my ability to enjoy sports and activities with a renewed zest.
“I absolutely lost the fight with my weight in my 40’s after two kids and a stressful job. Despite regular exercise and ongoing dieting I was carrying 20lbs I could not shed. After 3 months on Mounjaro, I lost 22 lbs. All of the muscle I’d built from my workouts finally started showing and I’ve never felt so confident about my body. Thank you to the JRNYS team!”
Being diagnosed with PCOS was a challenging chapter in my life. It led to an unexpected weight gain of over 30 pounds, along with acne, hair loss, insulin resistance, and relentless fatigue. But the tide turned when I started working with JRNYS and taking Ozempic. In just the first two weeks, I lost 10 pounds, a change that felt nothing short of miraculous. Gradually, I returned to my normal weight, feeling a sense of relief and normalcy that had seemed out of reach. This journey wasn’t just about weight loss; it was about regaining control and balance in my life.
"I was never petite and was considered overweight by age 14. The challenge intensified after having three children and navigating the pandemic, leading to a significant struggle with weight loss. My turning point came with JRNYS, which reignited my internal motivation. I was prescribed Mounjaro (the same drug as Zepbound/Tirzepatide), and the results have been transformative—I've lost over 40 pounds in the past seven months. This journey feels like just the beginning. I'm now enthusiastic about going to the gym and am on a path to completely revitalize my life."
"Initially, I weighed 185 pounds at a height of 5 feet 7 inches, and I was struggling with pre-diabetes and PCOS, urgently seeking effective solutions. Within a week of consulting my JRNYS doctors, they managed to get GLP-1 receptor agonists prescribed for me. Since embarking on this treatment program, I have experienced significant progress, losing close to 60 pounds to date. This journey has not only been about weight loss but also about regaining control over my health and confronting the challenges posed by pre-diabetes and PCOS head-on."
“My wife gave me shit for years because my core wasn’t strong enough to stand on a paddle board. Now that I’ve lost 60lbs and strengthened my core I look great but still can’t stand on a paddle board”.
"After the pandemic, I found myself at the heaviest weight I'd ever been, nearly 160 pounds. The impact of COVID-19 was severe, leaving me with fatigue that lasted almost three months. Determined to make a change, I committed to regular exercise and joined the JRNYS program. My doctors prescribed me Mounjaro (also known as Tirzepatide or Zepbound) and it worked within the first week. This combination of physical activity and structured guidance transformed my life. Remarkably, I managed to reduce my weight to 123 pounds and fit into a size 2, a milestone I had never achieved in my adult life. This journey was not just about losing weight; it was about overcoming unprecedented challenges and reaching a state of health and confidence I never thought possible."
Throughout my life, I never really focused on eating healthily or maintaining a fit lifestyle, and this started to take a toll on me in my 30s. I found myself unable to play sports with the same vigor and felt a general sense of slowing down. However, that all changed with the JRNYS program. Surprisingly, without any significant changes to my lifestyle other than the program, I managed to lose close to 30 pounds. This weight loss has given me a lot more energy, rejuvenating my ability to enjoy sports and activities with a renewed zest.
“I absolutely lost the fight with my weight in my 40’s after two kids and a stressful job. Despite regular exercise and ongoing dieting I was carrying 20lbs I could not shed. After 3 months on Mounjaro, I lost 22 lbs. All of the muscle I’d built from my workouts finally started showing and I’ve never felt so confident about my body. Thank you to the JRNYS team!”
Being diagnosed with PCOS was a challenging chapter in my life. It led to an unexpected weight gain of over 30 pounds, along with acne, hair loss, insulin resistance, and relentless fatigue. But the tide turned when I started working with JRNYS and taking Ozempic. In just the first two weeks, I lost 10 pounds, a change that felt nothing short of miraculous. Gradually, I returned to my normal weight, feeling a sense of relief and normalcy that had seemed out of reach. This journey wasn’t just about weight loss; it was about regaining control and balance in my life.
Effective GLP-1 treatment, without the waiting room.
Starting at $89/month. Provider-reviewed in 24 hours. Discreet shipping.
- Medication assisted weight loss with brands like Ozempic®† & Mounjaro®†
- Non Insurance Options
- Same day provider visits
- Up to 26% body fat loss*
- Personal coaching options
- 100% online consultations
*JRNYS members lost up to 26% of their body fat in a 6 month time period under our Mounjaro protocol.
†Disclaimer: Ozempic, Mounjaro and Zepbound are indicated for the treatment of type 2 diabetes but may be considered for off-label use in weight loss when suitable. Ozempic, Mounjaro and Zepbound carry the potential for severe side effects, including the risk of thyroid tumors. Do not utilize it if you or your family have a history of medullary thyroid carcinoma (MTC) or MEN 2.
Read more about Ozempic on serious side effects and safety information
Read more about Mounjaro on serious side effects and safety information
Read more about Zepbound on serious side effects and safety information
‡ JRNYS sends prescriptions and assists with prior authorizations when medically necessary, but does not accept or bill insurance directly. While our services help individuals manage their prescriptions by sending them to local pharmacies, it is these pharmacies that handle insurance claims.